Levamisole hydrochloride L-4 imidazole drug name, product is a four-imidazole hydrochloride L-body. Properties: white or light yellow crystalline powder, odorless, bitter taste with astringency. Soluble in water, methanol, slightly soluble in ethanol, very slightly soluble in chloroform, insoluble in acetone. Uses: selectively inhibit the parasite in muscle succinate dehydrogenase to fumarate to succinate can not reduction, affecting the anaerobic metabolism of muscle larvae, reduce energy production. When contact with parasites, can neuromuscular depolarization, sustained muscle contraction Erzhi paralysis occurs; drugs cholinergic function conducive to the discharge of worms. Its activity is about four imidazole (racemic) 1 ~ 2 times, but lower side effects. In addition, the drugs on parasite microtubules may inhibit it. Levamisole also excited immune and immune function. Of the roundworm, hookworm, Enterobius and Strongyloides stercoralis disease has a good effect. As a single dose of this product has high efficiency, it is suitable for group therapy |
